I've got QK SMTP 3 installed on an XP-Home, the first few times (maybe 4-6) I try to start up  the program (after Windows-startup) I get an error message saying that I should check if QK-SMTP wasn't running already..... which it never does....
 
Also: Options like "Auto run at Windows startup" are being completely ignored at the time of the next program startup.
 
I've already tried to deinstall and install the whole stueck, no success.... BTW, there is no spybot or anything like that installed on the mentioned machine, nothing that could block the registry.